Puerarin-loaded PEG-PE micelles with enhanced anti-apoptotic effect and better pharmacokinetic profile

Puerarin (PUE) is the most abundant isoflavonoid in kudzu root. It is widely used as a therapeutic agent for the treatment of cardiovascular diseases. However, the short elimination half-life, poor-bioavailability, and acute intravascular hemolysis of PUE are the main obstacles to its widespread cli...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Li, Wenqun, Wu, Junyong, Zhang, Jiang, Wang, Jingjing, Xiang, Daxiong, Luo, Shilin, Li, Jianhe, Liu, Xinyi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058490/
https://ncbi.nlm.nih.gov/pubmed/29587545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1455763
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