Control release of mitochondria-targeted antioxidant by injectable self-assembling peptide hydrogel ameliorated persistent mitochondrial dysfunction and inflammation after acute kidney injury

Persistent mitochondrial injury occurs after acute kidney injury (AKI) and mitochondria-targeted antioxidant Mito-2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPO) (MT) has shown benefits for AKI, but its efficiency is limited by short half-life and side effect in vivo. Self-assembling peptide (SAP) hydr...

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Gepubliceerd in:Drug Deliv
Hoofdauteurs: Zhao, Meng, Zhou, Yijie, Liu, Shuyun, Li, Lan, Chen, Younan, Cheng, Jingqiu, Lu, Yanrong, Liu, Jingping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058479/
https://ncbi.nlm.nih.gov/pubmed/29451033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1440445
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