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Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer

The synergistic combination of docetaxel (DTX) and cisplatin (CIS) by local drug delivery with a pluronic lecithin organogel (PLO) to facilitate high drug concentrations at tumor sites and less nonspecific distribution to normal organs is thought to be beneficial in chemotherapy. In this study, usin...

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Bibliografiske detaljer
Udgivet i:Drug Deliv
Main Authors: Chang, Chia-En, Hsieh, Chien-Ming, Chen, Ling-Chun, Su, Chia-Yu, Liu, Der-Zen, Jhan, Hua-Jing, Ho, Hsiu-O, Sheu, Ming-Thau
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058476/
https://ncbi.nlm.nih.gov/pubmed/29463123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1440444
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