Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer

The synergistic combination of docetaxel (DTX) and cisplatin (CIS) by local drug delivery with a pluronic lecithin organogel (PLO) to facilitate high drug concentrations at tumor sites and less nonspecific distribution to normal organs is thought to be beneficial in chemotherapy. In this study, usin...

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Publicado en:Drug Deliv
Autores principales: Chang, Chia-En, Hsieh, Chien-Ming, Chen, Ling-Chun, Su, Chia-Yu, Liu, Der-Zen, Jhan, Hua-Jing, Ho, Hsiu-O, Sheu, Ming-Thau
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058476/
https://ncbi.nlm.nih.gov/pubmed/29463123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1440444
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