The reversal effect of prothrombin complex concentrate (PCC), activated PCC and recombinant activated factor VII in apixaban‐treated patients in vitro

ESSENTIALS: An antidote for apixaban is not yet available. We tested the effect of different haemostatic agents to reverse the apixaban effect in vitro. Activated prothrombin complex concentrate (aPCC) was superior to prothrombin complex concentrate and recombinant activated factor VII. Even low dos...

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Publicado en:Res Pract Thromb Haemost
Autores principales: Schultz, Nina H., Tran, Hoa T. T., Bjørnsen, Stine, Henriksson, Carola E., Sandset, Per M., Holme, Pål A.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058213/
https://ncbi.nlm.nih.gov/pubmed/30046673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12015
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