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The reversal effect of prothrombin complex concentrate (PCC), activated PCC and recombinant activated factor VII against anticoagulation of Xa inhibitor

BACKGROUND: An increasing number of patients are treated with direct-acting oral anticoagulants (DOACs), but the optimal way to reverse the anticoagulant effect is not known. Specific antidotes are not available and prothrombin complex concentrate (PCC), activated PCC (aPCC) and recombinant factor V...

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Bibliografische gegevens
Gepubliceerd in:Thromb J
Hoofdauteurs: Schultz, Nina Haagenrud, Tran, Hoa Thi Tuyet, Bjørnsen, Stine, Henriksson, Carola Elisabeth, Sandset, Per Morten, Holme, Pål Andre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319105/
https://ncbi.nlm.nih.gov/pubmed/28239301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12959-017-0129-1
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