Effects of Sub-Chronic MPTP Exposure on Behavioral and Cognitive Performance and the Microbiome of Wild-Type and mGlu8 Knockout Female and Male Mice

Motor dysfunction is a hallmark of Parkinson’s disease (PD); however, non-motor symptoms such as gastrointestinal dysfunction often arise prior to motor symptoms. Alterations in the gut microbiome have been proposed as the earliest event in PD pathogenesis. PD symptoms often demonstrate sex differen...

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Detalles Bibliográficos
Publicado en:Front Behav Neurosci
Main Authors: Torres, Eileen Ruth S., Akinyeke, Tunde, Stagaman, Keaton, Duvoisin, Robert M., Meshul, Charles K., Sharpton, Thomas J., Raber, Jacob
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058038/
https://ncbi.nlm.nih.gov/pubmed/30072879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2018.00140
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