Effects of Sub-Chronic MPTP Exposure on Behavioral and Cognitive Performance and the Microbiome of Wild-Type and mGlu8 Knockout Female and Male Mice

Motor dysfunction is a hallmark of Parkinson’s disease (PD); however, non-motor symptoms such as gastrointestinal dysfunction often arise prior to motor symptoms. Alterations in the gut microbiome have been proposed as the earliest event in PD pathogenesis. PD symptoms often demonstrate sex differen...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Torres, Eileen Ruth S., Akinyeke, Tunde, Stagaman, Keaton, Duvoisin, Robert M., Meshul, Charles K., Sharpton, Thomas J., Raber, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058038/
https://ncbi.nlm.nih.gov/pubmed/30072879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2018.00140
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