Effects of Sub-Chronic MPTP Exposure on Behavioral and Cognitive Performance and the Microbiome of Wild-Type and mGlu8 Knockout Female and Male Mice

Motor dysfunction is a hallmark of Parkinson’s disease (PD); however, non-motor symptoms such as gastrointestinal dysfunction often arise prior to motor symptoms. Alterations in the gut microbiome have been proposed as the earliest event in PD pathogenesis. PD symptoms often demonstrate sex differen...

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Veröffentlicht in:Front Behav Neurosci
Hauptverfasser: Torres, Eileen Ruth S., Akinyeke, Tunde, Stagaman, Keaton, Duvoisin, Robert M., Meshul, Charles K., Sharpton, Thomas J., Raber, Jacob
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058038/
https://ncbi.nlm.nih.gov/pubmed/30072879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2018.00140
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