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A diverse lipid antigen-specific T cell receptor repertoire is clonally expanded during active tuberculosis
Human T cells that recognize lipid antigens presented by highly conserved CD1 proteins often express semi-invariant T cell receptors (TCRs), but the true diversity of lipid antigen-specific TCRs remains unknown. We use CD1b tetramers and high-throughput immunosequencing to analyze thousands of TCRs...
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| Publié dans: | J Immunol |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6057832/ https://ncbi.nlm.nih.gov/pubmed/29914888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800186 |
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