A diverse lipid antigen-specific T cell receptor repertoire is clonally expanded during active tuberculosis

Human T cells that recognize lipid antigens presented by highly conserved CD1 proteins often express semi-invariant T cell receptors (TCRs), but the true diversity of lipid antigen-specific TCRs remains unknown. We use CD1b tetramers and high-throughput immunosequencing to analyze thousands of TCRs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: DeWitt, William S., Yu, Krystle K.Q., Wilburn, Damien B., Sherwood, Anna, Vignali, Marissa, Day, Cheryl L., Scriba, Thomas J., Robins, Harlan S., Swanson, Willie J., Emerson, Ryan O., Bradley, Philip H., Seshadri, Chetan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057832/
https://ncbi.nlm.nih.gov/pubmed/29914888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800186
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