Neurexin directs partner-specific synaptic connectivity in C. elegans

In neural circuits, individual neurons often make projections onto multiple postsynaptic partners. Here, we investigate molecular mechanisms by which these divergent connections are generated, using dyadic synapses in C. elegans as a model. We report that C. elegans nrx-1/neurexin directs divergent...

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Pubblicato in:eLife
Autori principali: Philbrook, Alison, Ramachandran, Shankar, Lambert, Christopher M, Oliver, Devyn, Florman, Jeremy, Alkema, Mark J, Lemons, Michele, Francis, Michael M
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057746/
https://ncbi.nlm.nih.gov/pubmed/30039797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35692
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