Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice

Resistance and tolerance to infection are two universal fitness and survival strategies used by inflammation and immunity in organisms and cells to guard homeostasis. During sepsis, however, both strategies fail, and animal and human victims often die from combined innate and adaptive immune suppres...

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Bibliographic Details
Published in:J Immunol Res
Main Authors: Martin, Ayana N., Alexander-Miller, Martha, Yoza, Barbara K., Vachharajani, Vidula, McCall, Charles E.
Format: Artigo
Language:Inglês
Published: Hindawi 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057336/
https://ncbi.nlm.nih.gov/pubmed/30069485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2402593
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