High Circulating Caspase-Cleaved Keratin 18 Fragments (M30) Indicate Short-Term Mortality in Critically Ill Patients

Caspase-cleaved fragments of the intermediate filament protein keratin 18 (cytokeratin-18 (CK18)) can be detected in serum as M30 levels and may serve as a circulating biomarker indicating apoptosis of epithelial and parenchymal cells. In order to evaluate M30 as a biomarker in critical illness, we...

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Vydáno v:Dis Markers
Hlavní autoři: Koch, Alexander, Yagmur, Eray, Linka, Janine, Schumacher, Fabienne, Bruensing, Jan, Buendgens, Lukas, Herbers, Ulf, Koek, Ger H., Weiskirchen, Ralf, Trautwein, Christian, Tacke, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057335/
https://ncbi.nlm.nih.gov/pubmed/30069276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8583121
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