C-terminal proendothelin-1 (CT-proET-1) is associated with organ failure and predicts mortality in critically ill patients

BACKGROUND: Endothelin 1 (ET-1) is a strong vasoconstrictor, which is involved in inflammation and reduced tissue perfusion. C-terminal proendothelin-1 (CT-proET-1) is the stable circulating precursor protein of ET-1. We hypothesized that CT-proET-1, reflecting ET-1 activation, is involved in the pa...

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Detalhes bibliográficos
Publicado no:J Intensive Care
Main Authors: Buendgens, Lukas, Yagmur, Eray, Bruensing, Jan, Herbers, Ulf, Baeck, Christer, Trautwein, Christian, Koch, Alexander, Tacke, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359904/
https://ncbi.nlm.nih.gov/pubmed/28331622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40560-017-0219-y
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