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Advances in methods for reducing mitochondrial DNA disease by replacing or manipulating the mitochondrial genome
Mitochondrial DNA (mtDNA) is a multi-copy genome whose cell copy number varies depending on tissue type. Mutations in mtDNA can cause a wide spectrum of diseases. Mutated mtDNA is often found as a subset of the total mtDNA population in a cell or tissue, a situation known as heteroplasmy. As mitocho...
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| Publicado no: | Essays Biochem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056713/ https://ncbi.nlm.nih.gov/pubmed/29950320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20170113 |
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