Mitochondrial DNA Manipulations Affect Tau Oligomerization

Mitochondrial dysfunction and tau aggregation occur in Alzheimer’s disease (AD) and exposing cells or rodents to mitochondrial toxins alters their tau. To further explore how mitochondria influence tau, we measured tau oligomer levels in human neuronal SH-SY5Y cells with different mitochondrial DNA...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Weidling, Ian W., Wilkins, Heather M., Koppel, Scott J., Hutfles, Lewis, Wang, Xiaowan, Kalani, Anuradha, Menta, Blaise W., Ryan, Benjamin, Perez-Ortiz, Judit, Gamblin, T. Chris, Swerdlow, Russell H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962146/
https://ncbi.nlm.nih.gov/pubmed/32804126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200286
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