Mitochondrial DNA Manipulations Affect Tau Oligomerization

Mitochondrial dysfunction and tau aggregation occur in Alzheimer’s disease (AD) and exposing cells or rodents to mitochondrial toxins alters their tau. To further explore how mitochondria influence tau, we measured tau oligomer levels in human neuronal SH-SY5Y cells with different mitochondrial DNA...

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Dades bibliogràfiques
Publicat a:J Alzheimers Dis
Autors principals: Weidling, Ian W., Wilkins, Heather M., Koppel, Scott J., Hutfles, Lewis, Wang, Xiaowan, Kalani, Anuradha, Menta, Blaise W., Ryan, Benjamin, Perez-Ortiz, Judit, Gamblin, T. Chris, Swerdlow, Russell H.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962146/
https://ncbi.nlm.nih.gov/pubmed/32804126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200286
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