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Overexpression of PEAK1 contributes to epithelial–mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling

Pseudopodium-enriched atypical kinase 1 (PEAK1), a novel non-receptor tyrosine kinase, has been demonstrated to act as an oncogenic regulator in breast and pancreatic cancers. However, the role of PEAK1 in the progression and metastasis of lung cancer is still unknown. Here, we observed that ectopic...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ding, Chenbo, Tang, Wendong, Fan, Xiaobo, Wang, Xiyong, Wu, Hairu, Xu, Hongbo, Xu, Wei, Gao, Wei, Wu, Guoqiu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056550/
https://ncbi.nlm.nih.gov/pubmed/30038287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0817-1
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