Long noncoding RNA Sox2ot and transcription factor YY1 co-regulate the differentiation of cortical neural progenitors by repressing Sox2

Long noncoding RNAs (lncRNAs) are emerging as key regulators of crucial cellular processes. However, the molecular mechanisms of many lncRNA functions remain uncharacterized. Sox2ot is an evolutionarily conserved lncRNA that transcriptionally overlaps the pluripotency gene Sox2, which maintains the...

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Udgivet i:Cell Death Dis
Main Authors: Knauss, Jennifer L., Miao, Nan, Kim, Seung-Nam, Nie, Yanzhen, Shi, Yuelin, Wu, Tao, Pinto, Hugo Borges, Donohoe, Mary E., Sun, Tao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056501/
https://ncbi.nlm.nih.gov/pubmed/30038234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0840-2
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