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A novel calix[4]pyrrole derivative as a potential anticancer agent that forms genotoxic adducts with DNA
meso-(p-acetamidophenyl)-calix[4]pyrrole 3 was found to exhibit remarkable cytotoxicity towards A549 cancer cells. A comparative study including the isomer of 3 meso-(m-acetamidophenyl)-calix[4]pyrrole 5, as well as molecules containing ‘fragments’ of these structures, demonstrated that both the cal...
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| Gepubliceerd in: | Sci Rep |
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| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056420/ https://ncbi.nlm.nih.gov/pubmed/30038406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29314-9 |
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