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GDF11 induces kidney fibrosis, renal cell epithelial-to-mesenchymal transition and kidney dysfunction and failure
INTRODUCTION: GDF11 modulates embryonic patterning and kidney organogenesis. Herein, we sought to define GDF11 function in the adult kidney and in renal diseases. METHODS: In vitro renal cell lines, genetic and murine in vivo renal injury models were examined. RESULTS: Among tissues tested, Gdf11 wa...
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| Publié dans: | Surgery |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056317/ https://ncbi.nlm.nih.gov/pubmed/29731246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2018.03.008 |
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