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Gating mechanisms during actin filament elongation by formins

Formins play an important role in the polymerization of unbranched actin filaments, and particular formins slow elongation by 5–95%. We studied the interactions between actin and the FH2 domains of formins Cdc12, Bni1 and mDia1 to understand the factors underlying their different rates of polymeriza...

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Pubblicato in:eLife
Autori principali: Aydin, Fikret, Courtemanche, Naomi, Pollard, Thomas D, Voth, Gregory A
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056239/
https://ncbi.nlm.nih.gov/pubmed/30035712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37342
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