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Cryo-EM structure of the polycystin 2-l1 ion channel

We report the near atomic resolution (3.3 Å) of the human polycystic kidney disease 2-like 1 (polycystin 2-l1) ion channel. Encoded by PKD2L1, polycystin 2-l1 is a calcium and monovalent cation-permeant ion channel in primary cilia and plasma membranes. The related primary cilium-specific polycystin...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hulse, Raymond E, Li, Zongli, Huang, Rick K, Zhang, Jin, Clapham, David E
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056229/
https://ncbi.nlm.nih.gov/pubmed/30004384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36931
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