Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions

Bones at different anatomical locations vary dramatically in size. For example, human femurs are 20-fold longer than the phalanges in the fingers and toes. The mechanisms responsible for these size differences are poorly understood. Bone elongation occurs at the growth plates and advances rapidly in...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Lui, Julian C., Jee, Youn Hee, Garrison, Presley, Iben, James R., Yue, Shanna, Ad, Michal, Nguyen, Quang, Kikani, Bijal, Wakabayashi, Yoshiyuki, Baron, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Short Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056026/
https://ncbi.nlm.nih.gov/pubmed/30036371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005263
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