Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions

Bones at different anatomical locations vary dramatically in size. For example, human femurs are 20-fold longer than the phalanges in the fingers and toes. The mechanisms responsible for these size differences are poorly understood. Bone elongation occurs at the growth plates and advances rapidly in...

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Библиографические подробности
Опубликовано в: :PLoS Biol
Главные авторы: Lui, Julian C., Jee, Youn Hee, Garrison, Presley, Iben, James R., Yue, Shanna, Ad, Michal, Nguyen, Quang, Kikani, Bijal, Wakabayashi, Yoshiyuki, Baron, Jeffrey
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Short Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056026/
https://ncbi.nlm.nih.gov/pubmed/30036371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005263
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