The genomic landscape and pharmacogenomic interactions of clock genes in cancer chronotherapy

Cancer chronotherapy, treatment at specific times during circadian rhythms, endeavors to optimize anti-tumor effects and lower toxicity. However, comprehensive characterization of clock genes and their clinical relevance in cancer is lacking. We systematically characterized the alterations of clock...

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Veröffentlicht in:Cell Syst
Hauptverfasser: Ye, Youqiong, Xiang, Yu, Ozguc, Fatma Muge, Kim, Yoonjin, Liu, Chun-Jie, Park, Peter K., Hu, Qingsong, Diao, Lixia, Lou, Yanyan, Lin, Chunru, Guo, An-Yuan, Zhou, Bingying, Wang, Li, Chen, Zheng, Takahashi, Joseph S., Mills, Gordon B., Yoo, Seung-Hee, Han, Leng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056007/
https://ncbi.nlm.nih.gov/pubmed/29525205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.01.013
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