Increased alcohol seeking in mice lacking Gpr88 involves dysfunctional mesocorticolimbic networks

BACKGOUND: Alcohol Use Disorders (AUDs) are devastating and poorly treated, and innovative targets are actively sought for prevention and treatment. The orphan G protein-coupled receptor GPR88 is enriched in mesocorticolimbic pathways, and Gpr88 knockout mice show hyperactivity and risk-taking behav...

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Publicat a:Biol Psychiatry
Autors principals: Ben Hamida, Sami, Mendonça-Netto, Sueli, Arefin, Tanzil Mahmud, Nasseef, Md. Taufiq, Boulos, Laura-Joy, McNicholas, Michael, Ehrlich, Aliza Toby, Clarke, Eleanor, Moquin, Luc, Gratton, Alain, Darcq, Emmanuel, Adela, Harsan Laura, Maldonado, Rafael, Kieffer, Brigitte Lina
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054571/
https://ncbi.nlm.nih.gov/pubmed/29580570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.01.026
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