Dysregulation of serum bile acids and FGF19 in alcoholic hepatitis

BACKGROUND & AIMS: The degree of cholestasis is an important disease driver in alcoholic hepatitis, a severe clinical condition that needs new biomarkers and targeted therapies. The mechanisms and biomarkers linked to cholestasis are largely unknown. METHODS: Here, we analyzed a well characteriz...

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Vydáno v:J Hepatol
Hlavní autoři: Brandl, Katharina, Hartmann, Phillipp, Jih, Lily J., Pizzo, Donald P., Argemi, Josepmaria, Ventura-Cots, Meritxell, Coulter, Sally, Liddle, Christopher, Ling, Lei, Rossi, Stephen J., DePaoli, Alex M., Loomba, Rohit, Mehal, Wajahat Z., Fouts, Derrick E., Lucey, Michael R., Bosques-Padilla, Francisco, Mathurin, Philippe, Louvet, Alexander, Garcia-Tsao, Guadalupe, Verna, Elizabeth C., Abraldes, Juan G., Brown, Robert S., Vargas, Victor, Altamirano, Jose, Caballería, Juan, Shawcross, Debbie, Stärkel, Peter, Ho, Samuel B., Bataller, Ramon, Schnabl, Bernd
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054564/
https://ncbi.nlm.nih.gov/pubmed/29654817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2018.03.031
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