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CRISPR Genome Surgery in the Retina in Light of Off-Targeting

PURPOSE OF REVIEW: Recent concerns regarding the clinical utilization of clustered regularly interspaced short palindromic repeats (CRISPR) involve uncertainties about the potential detrimental effects that many arise due to unintended genetic changes, as in off-target mutagenesis, during CRISPR gen...

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Bibliografische gegevens
Gepubliceerd in:Retina
Hoofdauteurs: Cho, Galaxy Y., Schaefer, Kellie A., Bassuk, Alexander G., Tsang, Stephen H., Mahajan, Vinit B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054556/
https://ncbi.nlm.nih.gov/pubmed/29746416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IAE.0000000000002197
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