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CRISPR Genome Surgery in the Retina in Light of Off-Targeting

PURPOSE OF REVIEW: Recent concerns regarding the clinical utilization of clustered regularly interspaced short palindromic repeats (CRISPR) involve uncertainties about the potential detrimental effects that many arise due to unintended genetic changes, as in off-target mutagenesis, during CRISPR gen...

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Bibliografski detalji
Izdano u:Retina
Glavni autori: Cho, Galaxy Y., Schaefer, Kellie A., Bassuk, Alexander G., Tsang, Stephen H., Mahajan, Vinit B.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054556/
https://ncbi.nlm.nih.gov/pubmed/29746416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IAE.0000000000002197
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