Phasevarions of bacterial pathogens: methylomics sheds new light on old enemies

A wide variety of bacterial pathogens express phase-variable DNA methyltransferases that control expression of multiple genes via epigenetic mechanisms. These randomly switching regulons – phasevarions – regulate genes involved in pathogenesis, host-adaptation and antibiotic resistance. Individual p...

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Bibliographic Details
Published in:Trends Microbiol
Main Authors: Atack, John M., Tan, Aimee, Bakaletz, Lauren O., Jennings, Michael P., Seib, Kate L.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054543/
https://ncbi.nlm.nih.gov/pubmed/29452952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2018.01.008
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