A survey of Type III restriction-modification systems reveals numerous, novel epigenetic regulators controlling phase-variable regulons; phasevarions

Many bacteria utilize simple DNA sequence repeats as a mechanism to randomly switch genes on and off. This process is called phase variation. Several phase-variable N(6)-adenine DNA-methyltransferases from Type III restriction-modification systems have been reported in bacterial pathogens. Random sw...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Atack, John M, Yang, Yuedong, Seib, Kate L, Zhou, Yaoqi, Jennings, Michael P
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909438/
https://ncbi.nlm.nih.gov/pubmed/29554328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky192
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