Mechano-redox control of integrin de-adhesion

How proteins harness mechanical force to control function is a significant biological question. Here we describe a human cell surface receptor that couples ligand binding and force to trigger a chemical event which controls the adhesive properties of the receptor. Our studies of the secreted platele...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Passam, Freda, Chiu, Joyce, Ju, Lining, Pijning, Aster, Jahan, Zeenat, Mor-Cohen, Ronit, Yeheskel, Adva, Kolšek, Katra, Thärichen, Lena, Aponte-Santamaría, Camilo, Gräter, Frauke, Hogg, Philip J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Biochemistry and Chemical Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054529/
https://ncbi.nlm.nih.gov/pubmed/29932420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34843
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