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A Compartmentalized Type I Interferon Response in the Gut During Chronic HIV-1 Infection is Associated with Immunopathogenesis

OBJECTIVE(S): Type I IFN (IFN-I) responses confer both protective and pathogenic effects in persistent virus infections. IFN-I diversity, stage of infection and tissue compartment may account for this dichotomy. The gut is a major site of early HIV-1 replication and microbial translocation, but the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:AIDS
Main Authors: DILLON, Stephanie M., GUO, Kejun, AUSTIN, Gregory L., GIANELLA, Sara, ENGEN, Phillip A, MUTLU, Ece A., LOSURDO, John, SWANSON, Garth, CHAKRADEO, Prachi, KESHAVARZIAN, Ali, LANDAY, Alan L., SANTIAGO, Mario L., WILSON, Cara C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054446/
https://ncbi.nlm.nih.gov/pubmed/29762170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001863
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