Membrane-Initiated Estrogen Receptor Signaling Mediates Metabolic Homeostasis via Central Activation of Protein Phosphatase 2A

Women gain weight and their diabetes risk increases as they transition through menopause; these changes can be partly reversed by hormone therapy. However, the underlying molecular mechanisms mediating these effects are unknown. A novel knock-in mouse line with the selective blockade of the membrane...

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Udgivet i:Diabetes
Main Authors: Ueda, Kazutaka, Takimoto, Eiki, Lu, Qing, Liu, Pangyen, Fukuma, Nobuaki, Adachi, Yusuke, Suzuki, Ryo, Chou, Shengpu, Baur, Wendy, Aronovitz, Mark J., Greenberg, Andrew S., Komuro, Issei, Karas, Richard H.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2018
Fag:
Obesity Studies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054435/
https://ncbi.nlm.nih.gov/pubmed/29764860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-1342
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