An Engineered Complement Factor H Construct for Treatment of C3 Glomerulopathy

Background C3 glomerulopathy (C3G) is associated with dysregulation of the alternative pathway of complement activation, and treatment options for C3G remain limited. Complement factor H (FH) is a potent regulator of the alternative pathway and might offer a solution, but the mass and complexity of...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Soc Nephrol
Egile Nagusiak: Yang, Yi, Denton, Harriet, Davies, Owen R., Smith-Jackson, Kate, Kerr, Heather, Herbert, Andrew P., Barlow, Paul N., Pickering, Matthew C., Marchbank, Kevin J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2018
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054357/
https://ncbi.nlm.nih.gov/pubmed/29588430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017091006
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