Daptomycin selects for genetic and phenotypic adaptations leading to antibiotic tolerance in MRSA

OBJECTIVES: Daptomycin non-susceptibility in Staphylococcus aureus can emerge via the accumulation of single or multiple mutations, each resulting in a slight increase in the daptomycin MIC. The daptomycin-non-susceptible phenotype may include other features such as daptomycin tolerance. This study...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Berti, Andrew D, Shukla, Neehal, Rottier, Aaron D, McCrone, J Sue, Turner, Hannah M, Monk, Ian R, Baines, Sarah L, Howden, Benjamin P, Proctor, Richard A, Rose, Warren E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054297/
https://ncbi.nlm.nih.gov/pubmed/29718242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky148
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