Methodological implementation of mixed linear models in multi-locus genome-wide association studies

The mixed linear model has been widely used in genome-wide association studies (GWAS), but its application to multi-locus GWAS analysis has not been explored and assessed. Here, we implemented a fast multi-locus random-SNP-effect EMMA (FASTmrEMMA) model for GWAS. The model is built on random single...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Wen, Yang-Jun, Zhang, Hanwen, Ni, Yuan-Li, Huang, Bo, Zhang, Jin, Feng, Jian-Ying, Wang, Shi-Bo, Dunwell, Jim M, Zhang, Yuan-Ming, Wu, Rongling
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Software Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054291/
https://ncbi.nlm.nih.gov/pubmed/28158525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbw145
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