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pKWmEB: integration of Kruskal–Wallis test with empirical Bayes under polygenic background control for multi-locus genome-wide association study

Although nonparametric methods in genome-wide association studies (GWAS) are robust in quantitative trait nucleotide (QTN) detection, the absence of polygenic background control in single-marker association in genome-wide scans results in a high false positive rate. To overcome this issue, we propos...

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Detalhes bibliográficos
Publicado no:Heredity (Edinb)
Main Authors: Ren, Wen-Long, Wen, Yang-Jun, Dunwell, Jim M., Zhang, Yuan-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836593/
https://ncbi.nlm.nih.gov/pubmed/29234158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41437-017-0007-4
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