Nitrite circumvents platelet resistance to nitric oxide in patients with heart failure preserved ejection fraction and chronic atrial fibrillation

AIMS: Heart failure (HF) is a pro-thrombotic state. Both platelet and vascular responses to nitric oxide (NO) donors are impaired in HF patients with reduced ejection fraction (HFrEF) compared with healthy volunteers (HVs) due to scavenging of NO, and possibly also reduced activity of the principal...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Borgognone, Alessandra, Shantsila, Eduard, Worrall, Sophie M, Prompunt, Eakkapote, Loka, Thomas, Loudon, Brodie L, Chimen, Myriam, Ed Rainger, G, Lord, Janet M, Turner, Ashley, Nightingale, Peter, Feelisch, Martin, Kirchhof, Paulus, Lip, Gregory Y H, Watson, Steve P, Frenneaux, Michael P, Madhani, Melanie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054254/
https://ncbi.nlm.nih.gov/pubmed/29659727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy087
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