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Acute inhibition of kappa opioid receptors before stress blocks depression-like behaviors in California mice

Kappa opioid receptors (KOR) are considered to be a promising therapeutic target for stress-induced psychiatric disorders such as anxiety and depression. Preclinical data show that KOR antagonists have greater efficacy if administered before stressful experiences as opposed to afterwards. However, a...

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Detalhes bibliográficos
Publicado no:Prog Neuropsychopharmacol Biol Psychiatry
Main Authors: Williams, Alexia V., Laman-Maharg, Abigail, Armstrong, Crystal V., Ramos-Maciel, Stephanie, Minie, Vanessa A., Trainor, Brian C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054130/
https://ncbi.nlm.nih.gov/pubmed/29879438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2018.06.001
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