Sex Differences in the Effects of a Kappa Opioid Receptor Antagonist in the Forced Swim Test

There is growing evidence that kappa opioid receptor (KOR) antagonists could be a useful class of therapeutics for treating depression and anxiety. However, the overwhelming majority of preclinical investigations examining the behavioral effects of KOR antagonists have been in male rodents. Here, we...

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Publicado en:Front Pharmacol
Autores principales: Laman-Maharg, Abigail, Williams, Alexia V., Zufelt, Mikaela D., Minie, Vanessa A., Ramos-Maciel, Stephanie, Hao, Rebecca, Ordoñes Sanchez, Evelyn, Copeland, Tiffany, Silverman, Jill L., Leigh, Angelina, Snyder, Rodney, Carroll, F. Ivy, Fennell, Timothy R., Trainor, Brian C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817081/
https://ncbi.nlm.nih.gov/pubmed/29491835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00093
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