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Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling

Upon gastrulation, the mammalian conceptus transforms rapidly from a simple bilayer into a multilayered embryo enveloped by its extra-embryonic membranes. Impaired development of the amnion, the innermost membrane, causes major malformations. To clarify the origin of the mouse amnion, we used single...

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Vydáno v:Development
Hlavní autoři: Dobreva, Mariya P., Abon Escalona, Vanesa, Lawson, Kirstie A., Sanchez, Marina N., Ponomarev, Ljuba C., Pereira, Paulo N. G., Stryjewska, Agata, Criem, Nathan, Huylebroeck, Danny, Chuva de Sousa Lopes, Susana M., Aerts, Stein, Zwijsen, An
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053664/
https://ncbi.nlm.nih.gov/pubmed/29884675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.157222
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