NGR (Asn-Gly-Arg)-targeted delivery of coagulase to tumor vasculature arrests cancer cell growth

Induction of selective thrombosis and infarction in tumor-feeding vessels represents an attractive strategy to combat cancer. Here we took advantage of the unique coagulation properties of staphylocoagulase and genetically engineered it to generate a new fusion protein with novel anti-cancer propert...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Seidi, Khaled, Jahanban-Esfahlan, Rana, Monhemi, Hassan, Zare, Peyman, Minofar, Babak, Daei Farshchi Adli, Amir, Farajzadeh, Davoud, Behzadi, Ramezan, Mesgari Abbasi, Mehran, Neubauer, Heidi A., Moriggl, Richard, Zarghami, Nosratollah, Javaheri, Tahereh
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053358/
https://ncbi.nlm.nih.gov/pubmed/29662195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0213-4
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