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Tunable molecular tension sensors reveal extension-based control of vinculin loading

Molecular tension sensors have contributed to a growing understanding of mechanobiology. However, the limited dynamic range and inability to specify the mechanical sensitivity of these sensors has hindered their widespread use in diverse contexts. Here, we systematically examine the components of te...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: LaCroix, Andrew S, Lynch, Andrew D, Berginski, Matthew E, Hoffman, Brenton D
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053308/
https://ncbi.nlm.nih.gov/pubmed/30024378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33927
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