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Paxillin phosphorylation at serine 273 and its effects on Rac, Rho and adhesion dynamics

Focal adhesions are protein complexes that anchor cells to the extracellular matrix. During migration, the growth and disassembly of these structures are spatiotemporally regulated, with new adhesions forming at the leading edge of the cell and mature adhesions disassembling at the rear. Signalling...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Tang, Kaixi, Boudreau, Colton G., Brown, Claire M., Khadra, Anmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053249/
https://ncbi.nlm.nih.gov/pubmed/29975690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006303
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