The RNA-Binding Protein HuR Posttranscriptionally Regulates IL-2 Homeostasis and CD4(+) Th2 Differentiation

Posttranscriptional gene regulation by RNA-binding proteins, such as HuR (elavl1), fine-tune gene expression in T cells, leading to powerful effects on immune responses. HuR can stabilize target mRNAs and/or promote translation by interacting with their 3′ untranslated region adenylate and uridylate...

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Publicado no:Immunohorizons
Main Authors: Techasintana, Patsharaporn, Ellis, Jason S., Glascock, Jacqueline, Gubin, Matthew M., Ridenhour, Suzanne E., Magee, Joseph D., Hart, Marcia L., Yao, Peng, Zhou, Hao, Whitney, Maryln S., Franklin, Craig L., Martindale, Jennifer L., Gorospe, Myriam, Davis, Wade J., Fox, Paul L., Li, Xiaoxia, Atasoy, Ulus
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052877/
https://ncbi.nlm.nih.gov/pubmed/30035254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1700017
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