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Abnormal T-Cell Development in the Thymus of Non-obese Diabetic Mice: Possible Relationship With the Pathogenesis of Type 1 Autoimmune Diabetes

Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of insulin-producing cells in the pancreas, by direct interactions with autoreactive pancreas infiltrating T lymphocytes (PILs). One of the most important animal models for this disease is the non-obese diabetic (NOD) mouse. Al...

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Библиографические подробности
Опубликовано в: :Front Endocrinol (Lausanne)
Главные авторы: Mendes-da-Cruz, Daniella A., Lemos, Julia P., Passos, Geraldo A., Savino, Wilson
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052664/
https://ncbi.nlm.nih.gov/pubmed/30050502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00381
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