Sphingosine-1-Phosphate Receptor 1 Is Involved in Non-Obese Diabetic Mouse Thymocyte Migration Disorders

NOD (non-obese diabetic) mice spontaneously develop type 1 diabetes following T cell-dependent destruction of pancreatic β cells. Several alterations are observed in the NOD thymus, including the presence of giant perivascular spaces (PVS) filled with single-positive (SP) CD4(+) and CD8(+) T cells t...

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Udgivet i:Int J Mol Sci
Main Authors: Lemos, Julia P., Smaniotto, Salete, Messias, Carolina V., Moreira, Otacilio C., Cotta-de-Almeida, Vinicius, Dardenne, Mireille, Savino, Wilson, Mendes-da-Cruz, Daniella A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983610/
https://ncbi.nlm.nih.gov/pubmed/29757216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051446
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