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Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice
Aging is the largest risk factor for cardiovascular disease, yet the molecular mechanisms underlying vascular aging remain unclear. Mitochondrial DNA (mtDNA) damage is linked to aging, but whether mtDNA damage or mitochondrial dysfunction is present and directly promotes vascular aging is unknown. F...
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| Publicado en: | Aging Cell |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052475/ https://ncbi.nlm.nih.gov/pubmed/29745022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12773 |
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