Shuffling the Neutral Drift of Unspecific Peroxygenase in Saccharomyces cerevisiae

Unspecific peroxygenase (UPO) is a highly promiscuous biocatalyst, and its selective mono(per)oxygenase activity makes it useful for many synthetic chemistry applications. Among the broad repertory of library creation methods for directed enzyme evolution, genetic drift allows neutral mutations to b...

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Bibliographic Details
Published in:Appl Environ Microbiol
Main Authors: Martin-Diaz, Javier, Paret, Carmen, García-Ruiz, Eva, Molina-Espeja, Patricia, Alcalde, Miguel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Enzymology and Protein Engineering
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052263/
https://ncbi.nlm.nih.gov/pubmed/29776931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00808-18
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