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Endocrine cell type sorting and mature architecture in the islets of Langerhans require expression of Roundabout receptors in β cells
Pancreatic islets of Langerhans display characteristic spatial architecture of their endocrine cell types. This architecture is critical for cell-cell communication and coordinated hormone secretion. Islet architecture is disrupted in type-2 diabetes. Moreover, the generation of architecturally corr...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052079/ https://ncbi.nlm.nih.gov/pubmed/30022126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29118-x |
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